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Blausen Medical
Blausen Medical

Blausen Medical

Medically accurate and informative 3D animations

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Psoriasis

Activated dendritic cells produce IL-23 that activates Th17 cells and promotes their survival, leading to an increase in proinflammatory cytokines of the IL-17 family. IL-17, TNF-α, and IL-23 stimulate keratinocyte proliferation. Inhibitors of IL-17 – ixekinumab, secukinumab -- and of the IL-17 receptor -- brodalumab - block Th17 mediated inflammation.

Duration: 00:49
Licence: CC - Attribution
Original Language: English
Published: 8/9/2019
Diseases and Conditions: Psoriasis
Format: 3D Animation

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Psoriasis

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